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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHKG1 All Species: 27.88
Human Site: S199 Identified Species: 51.11
UniProt: Q16816 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16816 NP_006204.1 387 45024 S199 A P E I I E C S M N E D H P G
Chimpanzee Pan troglodytes XP_001153926 382 44180 S194 A P E I I E C S M N E D H P G
Rhesus Macaque Macaca mulatta XP_001089751 387 44961 S199 A P E I I E C S M N E D H P G
Dog Lupus familis XP_546902 530 60068 S342 A P E I I E C S M N D D H P G
Cat Felis silvestris
Mouse Mus musculus P07934 388 44941 S199 A P E I I Q C S M D D G H P G
Rat Rattus norvegicus P13286 388 44996 S199 A P E I I Q C S M D E G H P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKI0 479 54184 T240 F P S P E W D T V T P E A K D
Frog Xenopus laevis Q9DG02 475 53914 T239 F P S P E W D T V T P E A K D
Zebra Danio Brachydanio rerio Q6DGS3 554 62366 K317 T R N F S A A K S L L N K K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00168 530 59901 A263 N P N K R I T A A E A L K H P
Honey Bee Apis mellifera XP_623113 415 47613 N198 A P E V L K C N M F E N A E G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787539 414 46709 S206 A P E M L K C S M G L E N I S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWL2 534 60474 A254 V G S A Y Y V A P E V L H R N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.2 98.9 69.2 N.A. 93.3 93.8 N.A. N.A. 31.1 31.7 29.4 N.A. 27.7 51.5 N.A. 49.5
Protein Similarity: 100 94.5 99.7 70.9 N.A. 97.6 97.9 N.A. N.A. 46.7 46.9 42.2 N.A. 44.1 68.4 N.A. 64.9
P-Site Identity: 100 100 100 93.3 N.A. 73.3 80 N.A. N.A. 6.6 6.6 0 N.A. 6.6 46.6 N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 26.6 26.6 6.6 N.A. 13.3 80 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. 25.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 62 0 0 8 0 8 8 16 8 0 8 0 24 0 0 % A
% Cys: 0 0 0 0 0 0 62 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 16 0 0 16 16 31 0 0 16 % D
% Glu: 0 0 62 0 16 31 0 0 0 16 39 24 0 8 0 % E
% Phe: 16 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 0 0 0 0 8 0 16 0 0 54 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 54 8 0 % H
% Ile: 0 0 0 47 47 8 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 8 0 16 0 8 0 0 0 0 16 24 0 % K
% Leu: 0 0 0 0 16 0 0 0 0 8 16 16 0 0 0 % L
% Met: 0 0 0 8 0 0 0 0 62 0 0 0 0 0 0 % M
% Asn: 8 0 16 0 0 0 0 8 0 31 0 16 8 0 8 % N
% Pro: 0 85 0 16 0 0 0 0 8 0 16 0 0 47 16 % P
% Gln: 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 8 0 0 0 0 0 0 0 0 8 0 % R
% Ser: 0 0 24 0 8 0 0 54 8 0 0 0 0 0 8 % S
% Thr: 8 0 0 0 0 0 8 16 0 16 0 0 0 0 0 % T
% Val: 8 0 0 8 0 0 8 0 16 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _